are there multiple types of brindle?

by Ash on Mon 20 Jun 2016, 8:07 pm

I don't know if there is or not..

But EVERYWHERE that I look says the being homozygous (double dominant) for brindle is lethal, and that brindle is a sex linked gene and males that would have brindle is also lethal...

I have my mouse Calli who is brindle and her accidental litter of 12 with a black solid colored male, and ALL the pups are brindle (some are just minimal marking brindle).
The 5 males are also brindle...

Are there multiple types/different genes that cause brindle?

by CallaLily on Mon 20 Jun 2016, 8:57 pm

From the Varieties of Mice page:

Lab name: Viable Yellow
Fancier name: Brindle, American Brindle, Tiger Brindle, etc.
Genotype: Avy/*
Chromosome: 2
Originated: Spontaneous mutation (transposon insertion)
Show class: Brindle
General description: Stripped similar to a tiger from head to tail. Less define stripes on the belly.

These brindles are genetically linked to obesity, therefore they are more prone to health problems caused by the extra weight such as heart issues, diabetes, infertility, shortened life span, among many other conditions. These brindles are more prone to food allergies and tumors as well. Brindles are among of the number one choice (along with hairless) for labs to use in cancer research because of how well they 'accept' and 'grow' tumors. This does NOT mean they 'will' have the problems mentioned, they are just more prone to them than most other varieties. It is very important to obtain this variety from a GOOD breeder as that will greatly help prevent these problems. Brindles from bad breeders, including pet shops, are MUCH more likely to suffer health issues.

Lab name: (non-agouti) Brindled
Fancier name: Brindled, Sex Linked Brindle, X-Brindle, English Brindle, etc.
Genotype: a/a Mobr/* Note that Brindled is Sex linked. Homozygous Brindled is lethal as well as brindled bucks.
Chromosome: Brindled is on the X chromosome.
Originated: Spontaneous mutation (point mutation)
Show class: Brindle
General description: Striped similar to a tiger from head to tail. Less define stripes on the belly. They can be any color with eyes to match. Stripes on English brindles usually get wider with age.

These Brindled mice do not have the same health issues as Brindle (description above). The health of the females is the same as any other mouse. They are, however, sex linked. This means that outside of a lab, only females survive. Males suffer from copper deficiency, anemia. They appear similar to himalayan mice, with points. However, these points are part of their skin (where as a himalayan has pointed fur, not skin). They also tend to have extremely curly (spiral) whiskers regardless of coat type

Here:
http://petmousefanciers.forumotion.com/t12-varieties-of-mice

by Ash on Mon 20 Jun 2016, 9:05 pm

Oh my god.
I have been looking everywhere for this, and it was right here...!!!

That explains it. Thank you so much.

I think that because she also only had yellow/yellow base colored pups that would mean she is A^vy A^vy ? (Homozygous viable yellow?)

by Brynne on Tue 21 Jun 2016, 9:18 am

The general mouse poulation in the U.S. doesn't have lethal brindled.

by Ash on Thu 30 Jun 2016, 12:24 am

So.. Um..
My pups that were CLEARLY brindle(as fuzzies you could see stripes before their light fizz came in, as pups/young adults they all had stripes), now that they are grown (about 6 weeks) they don't look super brindle-y/stripey and more...

I'll post pictures soon. (Been having computer problems)

by **Peachy** on Thu 30 Jun 2016, 1:24 am

A couple of my brindles did that too. So funny! In a litter of seven, there was two blacks and two undermarked brindles, and at 17 months the undermarked brindles both look like plain old yellow mice. I kinda like it. Smile

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